Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM213787'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM213787 (US9284315, 86) Show SMILES COc1ccc(cn1)-c1ccc2ncc3CN(C)C(=O)N(C4CCN(CC4)C(=O)[C@@H](C)O)c3c2n1 |r| Show InChI InChI=1S/C25H28N6O4/c1-15(32)24(33)30-10-8-18(9-11-30)31-23-17(14-29(2)25(31)34)13-26-20-6-5-19(28-22(20)23)16-4-7-21(35-3)27-12-16/h4-7,12-13,15,18,32H,8-11,14H2,1-3H3/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	7.5	25
ZUANZHU PHARMA CO., LTD. US Patent					Assay Description 1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...				US Patent US9284315 (2016) BindingDB Entry DOI: 10.7270/Q2NC6011
					More data for this Ligand-Target Pair