Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM236558'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM236558 (US9365572, 6) Show SMILES Cn1c(=O)n(-c2cccc(c2)C(F)(F)F)c2c3nc(ccc3ncc2c1=O)-c1ccc(N)nc1 Show InChI InChI=1S/C23H15F3N6O2/c1-31-21(33)15-11-28-17-7-6-16(12-5-8-18(27)29-10-12)30-19(17)20(15)32(22(31)34)14-4-2-3-13(9-14)23(24,25)26/h2-11H,1H3,(H2,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65.8	n/a	n/a	n/a	n/a	7.5	25
Xuanzhu Pharma Co., Ltd. US Patent					Assay Description Agents: 1-fold kinase buffer: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT). 4-fold kinase solution: PI3Kα kinase ...				US Patent US9365572 (2016) BindingDB Entry DOI: 10.7270/Q20C4TNC
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