Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50149046'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50149046 (CHEMBL3770892) Show SMILES Nc1cc(c(cn1)-c1nc(N2CCOCC2)c2ccc(Nc3ccccn3)cc2n1)C(F)(F)F Show InChI InChI=1S/C23H20F3N7O/c24-23(25,26)17-12-19(27)29-13-16(17)21-31-18-11-14(30-20-3-1-2-6-28-20)4-5-15(18)22(32-21)33-7-9-34-10-8-33/h1-6,11-13H,7-10H2,(H2,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	393	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human recombinant PI3K alpha by scintillation proximity radiometric assay				Eur J Med Chem 108: 644-54 (2016) Article DOI: 10.1016/j.ejmech.2015.11.038 BindingDB Entry DOI: 10.7270/Q2C53NQ5
					More data for this Ligand-Target Pair