Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50204096'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50204096 (CHEMBL3894691) Show SMILES [O-][N+](=O)c1cccc(c1)-c1ccc2ncnc(Nc3ccc(CC#N)cc3)c2c1 Show InChI InChI=1S/C22H15N5O2/c23-11-10-15-4-7-18(8-5-15)26-22-20-13-17(6-9-21(20)24-14-25-22)16-2-1-3-19(12-16)27(28)29/h1-9,12-14H,10H2,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	451	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Integrative Medicine Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using diC8 PIP2 as substrate after 80 mins by ADP-glo assay				Eur J Med Chem 122: 731-743 (2016) Article DOI: 10.1016/j.ejmech.2016.07.006 BindingDB Entry DOI: 10.7270/Q2KS6TJ6
					More data for this Ligand-Target Pair