Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50315439'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50315439 (4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...) Show SMILES COc1ccc2[nH]c(c(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C24H17NO5/c1-29-15-7-8-18-16(11-15)17(23(25-18)13-5-3-2-4-6-13)12-21-24(28)22-19(27)9-14(26)10-20(22)30-21/h2-12,25-27H,1H3/b21-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha				Bioorg Med Chem Lett 20: 2586-90 (2010) Article DOI: 10.1016/j.bmcl.2010.02.082 BindingDB Entry DOI: 10.7270/Q2FQ9WRX
					More data for this Ligand-Target Pair