Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50328072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50328072 (3-(4-(3-methoxyphenylamino)-1-methyl-1H-pyrazolo[3...) Show SMILES CNC(=O)c1cccc(c1)-c1nc(Nc2cccc(OC)c2)c2cnn(C)c2n1 Show InChI InChI=1S/C21H20N6O2/c1-22-21(28)14-7-4-6-13(10-14)18-25-19(17-12-23-27(2)20(17)26-18)24-15-8-5-9-16(11-15)29-3/h4-12H,1-3H3,(H,22,28)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha				Bioorg Med Chem Lett 20: 6048-51 (2010) Article DOI: 10.1016/j.bmcl.2010.08.067 BindingDB Entry DOI: 10.7270/Q2ST7Q28
					More data for this Ligand-Target Pair