Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50341495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341495 (CHEMBL1765465 | N-(5-(3-(1H-Pyrazol-3-yl)imidazo[1...) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncc(-c3cc[nH]n3)n2c1)c1ccccc1 Show InChI InChI=1S/C21H16N6O2S/c28-30(29,18-4-2-1-3-5-18)26-17-10-16(11-22-12-17)15-6-7-21-23-13-20(27(21)14-15)19-8-9-24-25-19/h1-14,26H,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha after 180 mins by luminescent assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair