Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50341496'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341496 (CHEMBL1765617 | N-(5-(3-(2H-Tetrazol-5-yl)imidazo[...) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncc(-c3nnn[nH]3)n2c1)c1ccccc1 Show InChI InChI=1S/C19H14N8O2S/c28-30(29,16-4-2-1-3-5-16)24-15-8-14(9-20-10-15)13-6-7-18-21-11-17(27(18)12-13)19-22-25-26-23-19/h1-12,24H,(H,22,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha after 180 mins by luminescent assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair