Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50341505'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341505 (2,4-Difluoro-N-(5-(3-(5-methyl-1,2,4-oxadiazol-3-y...) Show SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C21H14F2N6O3S/c1-12-26-21(27-32-12)18-10-25-20-5-2-13(11-29(18)20)14-6-16(9-24-8-14)28-33(30,31)19-4-3-15(22)7-17(19)23/h2-11,28H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha after 180 mins by luminescent assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair