Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50419755'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50419755 (CHEMBL1949911) Show SMILES C1CN(CCO1)c1nc(nc2sccc12)-c1cccc2[nH]ncc12 Show InChI InChI=1S/C17H15N5OS/c1-2-11(13-10-18-21-14(13)3-1)15-19-16(22-5-7-23-8-6-22)12-4-9-24-17(12)20-15/h1-4,9-10H,5-8H2,(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assay				J Med Chem 54: 7815-33 (2011) Article DOI: 10.1021/jm2007084 BindingDB Entry DOI: 10.7270/Q2057GCQ
					More data for this Ligand-Target Pair