Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50425226'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50425226 (CHEMBL2314580) Show SMILES Oc1cccc(c1)-c1nc(nc2N(CCc12)c1cc[nH]c(=O)c1)N1CCOCC1 Show InChI InChI=1S/C21H21N5O3/c27-16-3-1-2-14(12-16)19-17-5-7-26(15-4-6-22-18(28)13-15)20(17)24-21(23-19)25-8-10-29-11-9-25/h1-4,6,12-13,27H,5,7-11H2,(H,22,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol 4,5-bisphosphate as substrate				Bioorg Med Chem Lett 23: 673-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.112 BindingDB Entry DOI: 10.7270/Q2KS6SVT
					More data for this Ligand-Target Pair