Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50515754'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50515754 (CHEMBL4448759) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(Cn2cc3c(n2)c2ccccc2oc3=O)CC1 Show InChI InChI=1S/C30H38N4O4S/c1-19(2)22-15-24(20(3)4)29(25(16-22)21(5)6)39(36,37)34-13-11-32(12-14-34)18-33-17-26-28(31-33)23-9-7-8-10-27(23)38-30(26)35/h7-10,15-17,19-21H,11-14,18H2,1-6H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
School of Traditional Chinese Pharmacy Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111630 BindingDB Entry DOI: 10.7270/Q2W380Q5
					More data for this Ligand-Target Pair