Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform' and Ligand = 'BDBM188474'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform (Homo sapiens (Human))	BDBM188474 (US9670194, Ex. 22 (S)-2-(1-((6-amino-5-(3-methyl-1...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2ccccc2c(=O)n1-c1ccccc1F |r,wD:2.2,(4,.62,;2.67,1.39,;1.33,.62,;1.33,-.92,;2.67,-1.69,;4,-.92,;5.33,-1.69,;5.33,-3.23,;4,-4,;4,-5.54,;2.67,-3.23,;1.33,-4,;-.13,-3.52,;-1.04,-4.77,;-2.58,-4.77,;-.13,-6.01,;1.33,-5.54,;,1.39,;-1.33,.62,;-2.67,1.39,;-4,.62,;-5.33,1.39,;-5.33,2.93,;-4,3.7,;-2.67,2.93,;-1.33,3.7,;-1.33,5.24,;,2.93,;1.33,3.7,;2.67,2.93,;4,3.7,;4,5.24,;2.67,6.01,;1.33,5.24,;,6.01,)| Show InChI InChI=1S/C24H21FN8O2/c1-3-16(30-21-19(20(26)27-12-28-21)23-29-13(2)32-35-23)22-31-17-10-6-4-8-14(17)24(34)33(22)18-11-7-5-9-15(18)25/h4-12,16H,3H2,1-2H3,(H3,26,27,28,30)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
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