Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform' and Ligand = 'BDBM189829'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform (Homo sapiens (Human))	BDBM189829 (US9670194, Ex. 51 (S)-2-(1-((6-amino-5-(1-methyl-1...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1ccn(C)n1)c1nc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C22H23ClN8O/c1-3-14(27-20-18(19(24)25-11-26-20)16-9-10-30(2)29-16)21-28-15-6-4-5-13(23)17(15)22(32)31(21)12-7-8-12/h4-6,9-12,14H,3,7-8H2,1-2H3,(H3,24,25,26,27)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
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