Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform' and Ligand = 'BDBM189840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform (Homo sapiens (Human))	BDBM189840 (US9670194, Ex. 59 (S)-2-(1-((6-amino-5-(5-isopropy...) Show SMILES CC(C)c1nc(no1)-c1c(N)ncnc1N[C@@H](C)c1nc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C22H23ClN8O2/c1-10(2)21-29-19(30-33-21)16-17(24)25-9-26-18(16)27-11(3)20-28-14-6-4-5-13(23)15(14)22(32)31(20)12-7-8-12/h4-6,9-12H,7-8H2,1-3H3,(H3,24,25,26,27)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
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