Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM172644'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172644 (US9090628, 304) Show SMILES CCN1CCC(CC1)C1CCCN1c1ccc2-c3nc(cn3CCOc2c1)-c1nc(C)nn1C(C)C Show InChI InChI=1S/C28H39N7O/c1-5-32-13-10-21(11-14-32)25-7-6-12-34(25)22-8-9-23-26(17-22)36-16-15-33-18-24(30-27(23)33)28-29-20(4)31-35(28)19(2)3/h8-9,17-19,21,25H,5-7,10-16H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair