Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM179268'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM179268 (US9126948, 8) Show SMILES COc1c(cc(Cl)c(F)c1-c1cncc(c1)S(C)(=O)=O)C(C)Nc1ncnc(N)c1C#N Show InChI InChI=1S/C20H18ClFN6O3S/c1-10(28-20-14(6-23)19(24)26-9-27-20)13-5-15(21)17(22)16(18(13)31-2)11-4-12(8-25-7-11)32(3,29)30/h4-5,7-10H,1-3H3,(H3,24,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<20	n/a	n/a	n/a	n/a	6.7	25
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...				US Patent US9126948 (2015) BindingDB Entry DOI: 10.7270/Q2P849NB
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