Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM200637'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM200637 (US9227977, Compound (Ia)) Show SMILES Nc1ncnc2n(Cc3nc4cccc(C#CCOCCOCCO)c4c(=O)n3Cc3ccccc3C(F)(F)F)nc(-c3cc(O)cc(F)c3)c12 Show InChI InChI=1S/C35H29F4N7O5/c36-24-15-23(16-25(48)17-24)31-30-32(40)41-20-42-33(30)46(44-31)19-28-43-27-9-3-6-21(7-4-11-50-13-14-51-12-10-47)29(27)34(49)45(28)18-22-5-1-2-8-26(22)35(37,38)39/h1-3,5-6,8-9,15-17,20,47-48H,10-14,18-19H2,(H2,40,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Ltd. US Patent					Assay Description As a means of assessing PI3K δ activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of PI3K&#...				US Patent US9227977 (2016) BindingDB Entry DOI: 10.7270/Q2BZ64WZ
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