Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM200640'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM200640 (US9227977, Example 50) Show SMILES COCCOCCOCC#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc34)n(Cc3ccccc3F)c(=O)c12 Show InChI InChI=1S/C35H32FN7O5/c1-46-15-16-48-18-17-47-14-6-10-23-8-5-13-28-30(23)35(45)42(20-25-7-2-3-12-27(25)36)29(40-28)21-43-34-31(33(37)38-22-39-34)32(41-43)24-9-4-11-26(44)19-24/h2-5,7-9,11-13,19,22,44H,14-18,20-21H2,1H3,(H2,37,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Ltd. US Patent					Assay Description The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...				US Patent US9227977 (2016) BindingDB Entry DOI: 10.7270/Q2BZ64WZ
					More data for this Ligand-Target Pair