Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM255546'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM255546 (US9499523, 20) Show SMILES Nc1cnc(cn1)-n1c(nc2cccc(Cl)c2c1=O)[C@@H](Nc1ncnc(N)c1Cl)C1CC1 |r| Show InChI InChI=1S/C20H17Cl2N9O/c21-10-2-1-3-11-14(10)20(32)31(13-7-25-12(23)6-26-13)19(29-11)16(9-4-5-9)30-18-15(22)17(24)27-8-28-18/h1-3,6-9,16H,4-5H2,(H2,23,25)(H3,24,27,28,30)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.4	25
GILEAD SCIENCES, INC. US Patent					Assay Description The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...				US Patent US9499523 (2016) BindingDB Entry DOI: 10.7270/Q2S46QWR
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