Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM320537'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320537 (US10174035, Compound 81 | [6-Fluoro-5-(1-methyl-1H...) Show SMILES Cn1cc(cn1)-c1nc2[nH]c(nc2c(N2CCOCC2)c1F)C(=O)N1CCN(CC1)C1CCOCC1 Show InChI InChI=1S/C24H31FN8O3/c1-30-15-16(14-26-30)19-18(25)21(32-8-12-36-13-9-32)20-22(27-19)29-23(28-20)24(34)33-6-4-31(5-7-33)17-2-10-35-11-3-17/h14-15,17H,2-13H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
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