Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM320591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320591 (US10174035, Compound 134 | [4-(Morpholin-4-yl)pipe...) Show SMILES FC(F)(F)c1n[nH]cc1-c1cc(N2CCOCC2)c2nc([nH]c2n1)C(=O)N1CCC(CC1)N1CCOCC1 Show InChI InChI=1S/C24H29F3N8O3/c25-24(26,27)20-16(14-28-32-20)17-13-18(34-7-11-38-12-8-34)19-21(29-17)31-22(30-19)23(36)35-3-1-15(2-4-35)33-5-9-37-10-6-33/h13-15H,1-12H2,(H,28,32)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
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