Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM341228'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM341228 ((S)-2,4-diamino-6-((1-(5-(3-(3,3-difluoropyrrolidi...) Show SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(CCCN3CCC(F)(F)C3)c2c(=O)n1-c1ccccc1 Show InChI InChI=1S/C28H28F3N9O/c1-16(35-24-19(14-32)23(33)37-27(34)38-24)25-36-22-20(29)10-9-17(6-5-12-39-13-11-28(30,31)15-39)21(22)26(41)40(25)18-7-3-2-4-8-18/h2-4,7-10,16H,5-6,11-13,15H2,1H3,(H5,33,34,35,37,38)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...				US Patent US9765060 (2017) BindingDB Entry DOI: 10.7270/Q2DZ0BDH
					More data for this Ligand-Target Pair