Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM358072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM358072 (((2S,4R)-2-(3-(4-Amino-5-(1-(tetrahydro-2H-pyran-4...) Show SMILES Nc1ncnn2c(cc(-c3ccnn3C3CCOCC3)c12)-c1cccc(c1)[C@@H]1C[C@@H](O)CN1C(=O)C1CC1 |r| Show InChI InChI=1S/C28H31N7O3/c29-27-26-22(23-6-9-31-34(23)20-7-10-38-11-8-20)14-25(35(26)32-16-30-27)19-3-1-2-18(12-19)24-13-21(36)15-33(24)28(37)17-4-5-17/h1-3,6,9,12,14,16-17,20-21,24,36H,4-5,7-8,10-11,13,15H2,(H2,29,30,32)/t21-,24+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...				US Patent US10214537 (2019) BindingDB Entry DOI: 10.7270/Q2HH6NB2
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