Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM358714'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM358714 (2-(4-acetyl-3,3-dimethyl-2- oxopiperazin-1-yl)-4-(...) Show SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cc(ccc1C(=O)NCC#N)-c1cc(c2c(N)ncnn12)C(F)(F)F Show InChI InChI=1S/C24H23F3N8O3/c1-13(36)34-9-8-33(22(38)23(34,2)3)18-10-14(4-5-15(18)21(37)30-7-6-28)17-11-16(24(25,26)27)19-20(29)31-12-32-35(17)19/h4-5,10-12H,7-9H2,1-3H3,(H,30,37)(H2,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...				US Patent US10214537 (2019) BindingDB Entry DOI: 10.7270/Q2HH6NB2
					More data for this Ligand-Target Pair