Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50004534'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004534 (CHEMBL2216898) Show SMILES CC(Nc1ncnc2[nH]cnc12)c1cc2cccc(C)c2c(OC2CCN(C)CC2)n1 Show InChI InChI=1S/C23H27N7O/c1-14-5-4-6-16-11-18(15(2)28-22-20-21(25-12-24-20)26-13-27-22)29-23(19(14)16)31-17-7-9-30(3)10-8-17/h4-6,11-13,15,17H,7-10H2,1-3H3,(H2,24,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004534 (CHEMBL2216898) Show SMILES CC(Nc1ncnc2[nH]cnc12)c1cc2cccc(C)c2c(OC2CCN(C)CC2)n1 Show InChI InChI=1S/C23H27N7O/c1-14-5-4-6-16-11-18(15(2)28-22-20-21(25-12-24-20)26-13-27-22)29-23(19(14)16)31-17-7-9-30(3)10-8-17/h4-6,11-13,15,17H,7-10H2,1-3H3,(H2,24,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta in B-cells by proliferation assay				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair