Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50201725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50201725 (CHEMBL3948373) Show SMILES Nc1ncnc2n(nc(-c3cc(F)c4OCCNc4c3)c12)C1Cc2ccccc2C1 Show InChI InChI=1S/C22H19FN6O/c23-16-9-14(10-17-20(16)30-6-5-25-17)19-18-21(24)26-11-27-22(18)29(28-19)15-7-12-3-1-2-4-13(12)8-15/h1-4,9-11,15,25H,5-8H2,(H2,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) using biotinylated PIP2 as substrate in presence of streptavidin-APC by FRET assay				ACS Med Chem Lett 7: 1161-1166 (2016) Article DOI: 10.1021/acsmedchemlett.6b00356 BindingDB Entry DOI: 10.7270/Q29K4D6F
					More data for this Ligand-Target Pair