Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50389072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50389072 (CHEMBL2064341) Show SMILES Fc1ccc2n(C3CC3)c(Cc3nc(cc(=O)[nH]3)N3CCOCC3)nc2c1 Show InChI InChI=1S/C19H20FN5O2/c20-12-1-4-15-14(9-12)21-18(25(15)13-2-3-13)10-16-22-17(11-19(26)23-16)24-5-7-27-8-6-24/h1,4,9,11,13H,2-3,5-8,10H2,(H,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research& Development Curated by ChEMBL					Assay Description Inhibition of poly-His tagged human PI3Kdelta expressed in baculovirus infected insect sf9 cells coexpressing p85alpha using PI(4,5)P2 as substrate p...				J Med Chem 55: 4788-805 (2012) Article DOI: 10.1021/jm300241b BindingDB Entry DOI: 10.7270/Q2R78G88
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