Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50396643'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50396643 (CHEMBL2171947) Show SMILES CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2ccc(nc2n1)N1CCC(CC1)C(C)(C)O Show InChI InChI=1S/C28H35N7O2/c1-4-23-29-21-7-5-6-8-22(21)35(23)27-31-25-20(26(32-27)34-15-17-37-18-16-34)9-10-24(30-25)33-13-11-19(12-14-33)28(2,3)36/h5-10,19,36H,4,11-18H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of recombinant PI3Kdelta assessed as inhibition of PIP3 production for 30 mins by fluorescence polarization assay				J Med Chem 55: 7686-95 (2012) Article DOI: 10.1021/jm300717c BindingDB Entry DOI: 10.7270/Q2DB8302
					More data for this Ligand-Target Pair