Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50436449'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50436449 (CHEMBL2397188) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)Nc1nc(C)c(s1)-c1ccnc(c1)C(C)(C)C |r| Show InChI InChI=1S/C20H27N5O2S/c1-12-16(13-8-9-22-15(11-13)20(2,3)4)28-18(23-12)24-19(27)25-10-6-7-14(25)17(26)21-5/h8-9,11,14H,6-7,10H2,1-5H3,(H,21,26)(H,23,24,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of P110delta (unknown origin) using PIP2:PS as substrate by TR-FRET assay				Bioorg Med Chem Lett 23: 3741-8 (2013) Article DOI: 10.1016/j.bmcl.2013.05.007 BindingDB Entry DOI: 10.7270/Q2M046VD
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50436449 (CHEMBL2397188) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)Nc1nc(C)c(s1)-c1ccnc(c1)C(C)(C)C |r| Show InChI InChI=1S/C20H27N5O2S/c1-12-16(13-8-9-22-15(11-13)20(2,3)4)28-18(23-12)24-19(27)25-10-6-7-14(25)17(26)21-5/h8-9,11,14H,6-7,10H2,1-5H3,(H,21,26)(H,23,24,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of N-terminal myristoylated P110delta (unknown origin)-mediated AKT phosphorylation at Ser473 expressed in rat Rat1 cells by ELISA				Bioorg Med Chem Lett 23: 3741-8 (2013) Article DOI: 10.1016/j.bmcl.2013.05.007 BindingDB Entry DOI: 10.7270/Q2M046VD
					More data for this Ligand-Target Pair