Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM474020'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM474020 (US10858355, Example 28) Show SMILES C[C@@H](C1CC1)N1Cc2cc(cc(NS(=O)(=O)CC3CC3)c2C1=O)-c1sc(NC(C)=O)nc1C |r| Show InChI InChI=1S/C23H28N4O4S2/c1-12-21(32-23(24-12)25-14(3)28)17-8-18-10-27(13(2)16-6-7-16)22(29)20(18)19(9-17)26-33(30,31)11-15-4-5-15/h8-9,13,15-16,26H,4-7,10-11H2,1-3H3,(H,24,25,28)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...				US Patent US10858355 (2020) BindingDB Entry DOI: 10.7270/Q2BZ6945
					More data for this Ligand-Target Pair