Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50381160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50381160 (CHEMBL2018218) Show SMILES CSc1nn2c(nc(cc2=O)-c2ccncc2)n1Cc1cccc(Cl)c1Cl Show InChI InChI=1S/C18H13Cl2N5OS/c1-27-18-23-25-15(26)9-14(11-5-7-21-8-6-11)22-17(25)24(18)10-12-3-2-4-13(19)16(12)20/h2-9H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assay				Bioorg Med Chem Lett 22: 3198-202 (2012) Article DOI: 10.1016/j.bmcl.2012.03.039 BindingDB Entry DOI: 10.7270/Q2TD9ZBP
					More data for this Ligand-Target Pair