Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50448102'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50448102 (CHEMBL3121328) Show SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nc(N)c(cc2c1)-c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C31H27F2N5O4S/c1-41-31-28(37-43(39,40)29-9-5-23(32)17-26(29)33)16-22(18-35-31)20-4-8-27-21(14-20)15-25(30(34)36-27)19-2-6-24(7-3-19)38-10-12-42-13-11-38/h2-9,14-18,37H,10-13H2,1H3,(H2,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (2 to 1102) (unknown origin) using diC8-PIP2 as substrate preincubated for 30 mins followed by substrate addition measured af...				J Med Chem 57: 2091-106 (2014) Article DOI: 10.1021/jm400781h BindingDB Entry DOI: 10.7270/Q2WH2RG0
					More data for this Ligand-Target Pair