Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Phosphodiesterase' and Ligand = 'BDBM331979'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM331979 ((R)- or (S)-2- (3,4-dimethoxy- benzyl)-6-(1-(1- (2...) Show SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)-c2cn(cn2)C(C)c2ccc(cc2F)C(F)(F)F)cc1OC Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				US Patent US10195201 (2019) BindingDB Entry DOI: 10.7270/Q20G3N7K
					More data for this Ligand-Target Pair
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM331979 ((R)- or (S)-2- (3,4-dimethoxy- benzyl)-6-(1-(1- (2...) Show SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)-c2cn(cn2)C(C)c2ccc(cc2F)C(F)(F)F)cc1OC Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				US Patent US10195201 (2019) BindingDB Entry DOI: 10.7270/Q20G3N7K
					More data for this Ligand-Target Pair
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM331979 ((R)- or (S)-2- (3,4-dimethoxy- benzyl)-6-(1-(1- (2...) Show SMILES COc1ccc(Cc2nc(cc(=O)[nH]2)-c2cn(cn2)C(C)c2ccc(cc2F)C(F)(F)F)cc1OC Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				US Patent US10195201 (2019) BindingDB Entry DOI: 10.7270/Q20G3N7K
					More data for this Ligand-Target Pair