Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase' and Ligand = 'BDBM50427449'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Trypanosoma brucei)	BDBM50427449 (CHEMBL2326944) Show SMILES O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)N(Cc1ccco1)C1CC1 Show InChI InChI=1S/C24H22N2O4/c27-21(26(17-11-12-17)15-18-7-4-14-30-18)10-3-13-25-23(28)19-8-1-5-16-6-2-9-20(22(16)19)24(25)29/h1-2,4-9,14,17H,3,10-13,15H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei full length PDEB1 expressed in insect SF21 cells using cAMP as substrate by scintillation proximity assay				J Med Chem 56: 2087-96 (2013) Article DOI: 10.1021/jm3017877 BindingDB Entry DOI: 10.7270/Q2319X7M
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