Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phospholipase A2, major isoenzyme' and Ligand = 'BDBM23758'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, major isoenzyme (Sus scrofa (pig))	BDBM23758 (3-{4-[(4-hexadecylpiperazin-1-yl)carbonyl]phenyl}-...) Show SMILES CCCCCCCCCCCCCCCCN1CCN(CC1)C(=O)c1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C29H46N4O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20-32-21-23-33(24-22-32)28(34)26-18-16-25(17-19-26)27-30-29(35)36-31-27/h16-19H,2-15,20-24H2,1H3,(H,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	22
Universite Paris 7-Denis Diderot					Assay Description PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...				Bioorg Med Chem 16: 1242-53 (2008) Article DOI: 10.1016/j.bmc.2007.10.077 BindingDB Entry DOI: 10.7270/Q2J964PK
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