Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phospholipase D1 (Homo sapiens (Human)) | BDBM179733 (US9127005, NGH) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University US Patent | Assay Description In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo... | US Patent US9127005 (2015) BindingDB Entry DOI: 10.7270/Q2CV4GHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D1 (Homo sapiens (Human)) | BDBM179733 (US9127005, NGH) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of PLD1 in human Calu1 cells | Bioorg Med Chem Lett 28: 3670-3673 (2018) Article DOI: 10.1016/j.bmcl.2018.10.033 BindingDB Entry DOI: 10.7270/Q2HQ436Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D1 (Homo sapiens (Human)) | BDBM179733 (US9127005, NGH) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University US Patent | Assay Description In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo... | US Patent US9127005 (2015) BindingDB Entry DOI: 10.7270/Q2CV4GHP | |||||||||||
More data for this Ligand-Target Pair |