BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM306641'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))		BDBM306641
PNG
((1S,8R)-N-[(4- carbamimidoylphenyl) methyl]-12-(2-...)
Show SMILES CC(C)(F)c1ccc2[C@@H]3O[C@@H](c4cc(ccc34)C(=O)NCc3ccc(cc3)C(N)=N)c2c1 |r|
Show InChI InChI=1S/C26H24FN3O2/c1-26(2,27)17-8-10-19-21(12-17)23-20-11-16(7-9-18(20)22(19)32-23)25(31)30-13-14-3-5-15(6-4-14)24(28)29/h3-12,22-23H,13H2,1-2H3,(H3,28,29)(H,30,31)/t22-,23+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.31n/an/an/an/an/an/a



Global Blood Therapeutics, Inc.

US Patent


Assay Description
The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...

US Patent US10144746 (2018)


BindingDB Entry DOI: 10.7270/Q2J38VNH
More data for this
Ligand-Target Pair