Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM335860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM335860 ((S)-4-(2-(1-(3-Chloro-2-fluorophenyl)-1H-imidazole...) Show SMILES OC(=O)c1ccc(NC(=O)[C@H]2N(CCc3c2cccc3N2CCOCC2)C(=O)c2cn(cn2)-c2cccc(Cl)c2F)cc1 |r| Show InChI InChI=1S/C31H27ClFN5O5/c32-23-4-2-6-26(27(23)33)37-17-24(34-18-37)30(40)38-12-11-21-22(3-1-5-25(21)36-13-15-43-16-14-36)28(38)29(39)35-20-9-7-19(8-10-20)31(41)42/h1-10,17-18,28H,11-16H2,(H,35,39)(H,41,42)/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...				US Patent US9738655 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R3R
					More data for this Ligand-Target Pair