Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasminogen' and Ligand = 'BDBM50092334'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50092334 (4-({2-[(4-Aminomethyl-cyclohexanecarbonyl)-amino]-...) Show SMILES CCCCCCCCOC(=O)[C@H]1CC[C@H](CNC(=O)C(Cc2ccc(OC(=O)OCc3ccccc3Br)cc2)NC(=O)[C@H]2CC[C@H](CN)CC2)CC1 |wU:42.43,14.14,wD:11.10,45.47,(22.77,-3.21,;21.44,-2.44,;20.1,-3.21,;18.77,-2.44,;17.44,-3.21,;16.1,-2.44,;14.77,-3.21,;13.44,-2.44,;12.1,-3.21,;10.77,-2.44,;10.77,-.9,;9.44,-3.21,;8.1,-2.44,;6.77,-3.21,;6.77,-4.75,;5.43,-5.52,;4.1,-4.75,;2.77,-5.52,;2.77,-7.06,;1.43,-4.75,;1.43,-3.21,;.1,-2.44,;.1,-.9,;-1.23,-.13,;-2.57,-.9,;-3.9,-.13,;-3.9,1.41,;-2.57,2.18,;-5.24,2.18,;-5.24,3.72,;-6.57,4.49,;-7.9,3.72,;-9.24,4.49,;-9.24,6.03,;-7.9,6.8,;-6.57,6.03,;-5.24,6.8,;-2.57,-2.44,;-1.23,-3.21,;.1,-5.52,;.1,-7.06,;1.43,-7.83,;-1.23,-7.83,;-1.23,-9.37,;-2.57,-10.14,;-3.9,-9.37,;-5.24,-10.14,;-6.57,-9.37,;-3.9,-7.83,;-2.57,-7.06,;8.1,-5.52,;9.44,-4.75,)| Show InChI InChI=1S/C41H58BrN3O7/c1-2-3-4-5-6-9-24-50-40(48)33-20-14-31(15-21-33)27-44-39(47)37(45-38(46)32-18-12-30(26-43)13-19-32)25-29-16-22-35(23-17-29)52-41(49)51-28-34-10-7-8-11-36(34)42/h7-8,10-11,16-17,22-23,30-33,37H,2-6,9,12-15,18-21,24-28,43H2,1H3,(H,44,47)(H,45,46)/t30-,31-,32-,33-,37?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibitory activity of compound was evaluated against plasmin				Bioorg Med Chem Lett 10: 2217-21 (2001) BindingDB Entry DOI: 10.7270/Q2125RXQ
					More data for this Ligand-Target Pair