Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-activating factor acetylhydrolase IB subunit alpha2' and Ligand = 'BDBM50188244'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188244 (CHEMBL3828405) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(Br)cc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H58Br2ClN13O11S/c1-75-25-24-62(28-42(68)61(23-5-3-21-54)27-41(67)60(26-40(55)66)22-4-2-20-53)43(69)29-64(59-48(73)56-37-16-12-35(51)13-17-37)44(70)30-63(57-46(72)33-8-14-36(52)15-9-33)45(71)31-65-49(74)76-47(58-65)39-19-18-38(77-39)32-6-10-34(50)11-7-32/h6-19H,2-5,20-31,53-54H2,1H3,(H2,55,66)(H,57,72)(H2,56,59,73)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of FP-Rh probe binding to recombinant PAFAH1B2 (unknown origin) doped in human HeLa cell lysate incubated for 30 mins followed by FP-Rh pr...				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188244 (CHEMBL3828405) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(Br)cc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H58Br2ClN13O11S/c1-75-25-24-62(28-42(68)61(23-5-3-21-54)27-41(67)60(26-40(55)66)22-4-2-20-53)43(69)29-64(59-48(73)56-37-16-12-35(51)13-17-37)44(70)30-63(57-46(72)33-8-14-36(52)15-9-33)45(71)31-65-49(74)76-47(58-65)39-19-18-38(77-39)32-6-10-34(50)11-7-32/h6-19H,2-5,20-31,53-54H2,1H3,(H2,55,66)(H,57,72)(H2,56,59,73)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair