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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-activating factor receptor' and Ligand = 'BDBM50004621'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50004621
PNG
(4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-oxo-2,3-dihyd...)
Show SMILES CCOC(=O)C1=C(N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-n1c2ccncc2[nH]c1=O |t:5,7|
Show InChI InChI=1S/C33H27ClN6O4/c1-3-44-32(42)29-28(22-8-4-5-9-23(22)34)27(31(41)39-26-10-6-7-16-36-26)19(2)37-30(29)20-11-13-21(14-12-20)40-25-15-17-35-18-24(25)38-33(40)43/h4-18,27-28H,3H2,1-2H3,(H,38,43)(H,36,39,41)
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PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.

J Med Chem 35: 3115-29 (1992)


BindingDB Entry DOI: 10.7270/Q28W3DX8
More data for this
Ligand-Target Pair