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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-activating factor receptor' and Ligand = 'BDBM50062046'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50062046
PNG
(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Show SMILES CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)cc2)c2c(cccc12)C(O)=O
Show InChI InChI=1S/C27H23N5O4/c1-16-29-21-13-28-12-11-22(21)31(16)14-17-7-9-18(10-8-17)25(33)20-15-32(27(36)30(2)3)23-6-4-5-19(24(20)23)26(34)35/h4-13,15H,14H2,1-3H3,(H,34,35)
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 14n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes

J Med Chem 41: 74-95 (1998)


Article DOI: 10.1021/jm970389+
BindingDB Entry DOI: 10.7270/Q2MC8Z4D
More data for this
Ligand-Target Pair