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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50187343'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor alpha/beta


(Mus musculus (mouse))
BDBM50187343
PNG
((4-Bromo-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)-...)
Show SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2c(Br)cccc2[nH]1
Show InChI InChI=1S/C17H11BrN2O2/c18-12-2-1-3-14-11(12)8-16(20-14)17(22)15-7-9-6-10(21)4-5-13(9)19-15/h1-8,19-21H
MMDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts


J Med Chem 49: 3101-15 (2006)


Article DOI: 10.1021/jm058033i
BindingDB Entry DOI: 10.7270/Q26T0M7B
More data for this
Ligand-Target Pair