Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50187354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50187354 (CHEMBL377873 | [5-(2-Dimethylaminoethoxy)-1H-indol...) Show SMILES COc1ccc2cc([nH]c2c1)C(=O)c1cc2cc(OCCN(C)C)ccc2[nH]1 Show InChI InChI=1S/C22H23N3O3/c1-25(2)8-9-28-17-6-7-18-15(10-17)12-21(23-18)22(26)20-11-14-4-5-16(27-3)13-19(14)24-20/h4-7,10-13,23-24H,8-9H2,1-3H3	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
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