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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha' and Ligand = 'BDBM50184857'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50184857
PNG
(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC
Show InChI InChI=1S/C26H23N3O5/c1-16-6-4-5-7-19(16)25(30)29-26(31)28-17-8-10-18(11-9-17)34-22-12-13-27-21-15-24(33-3)23(32-2)14-20(21)22/h4-15H,1-3H3,(H2,28,29,30,31)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Kirin Brewery Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PDGFR alpha phosphorylation in G292 cell


J Med Chem 49: 2186-92 (2006)


Article DOI: 10.1021/jm0506423
BindingDB Entry DOI: 10.7270/Q2NC60TB
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50184857
PNG
(CHEMBL203227 | N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC
Show InChI InChI=1S/C26H23N3O5/c1-16-6-4-5-7-19(16)25(30)29-26(31)28-17-8-10-18(11-9-17)34-22-12-13-27-21-15-24(33-3)23(32-2)14-20(21)22/h4-15H,1-3H3,(H2,28,29,30,31)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.60n/an/an/an/an/an/a



Kirin Brewery Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of PDGFR alpha phosphorylation in G292 cell by transactivation enzyme assay


J Med Chem 49: 2186-92 (2006)


Article DOI: 10.1021/jm0506423
BindingDB Entry DOI: 10.7270/Q2NC60TB
More data for this
Ligand-Target Pair