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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4202'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM4202
PNG
(6-(2,6-dichlorophenyl)-2-{[2-(diethylamino)ethyl]a...)
Show SMILES CCN(CC)CCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 |(-12.59,.48,;-11.1,.88,;-10.01,-.21,;-10.78,-1.54,;-10.01,-2.88,;-8.53,-.61,;-7.19,.16,;-5.86,-.61,;-4.53,.16,;-4.53,1.7,;-3.19,2.47,;-1.86,1.7,;-.52,2.47,;.81,1.7,;2.14,2.47,;2.14,4.01,;.81,4.78,;3.48,4.78,;4.81,4.01,;4.81,2.47,;3.48,1.7,;3.48,.16,;.81,.16,;2.14,-.61,;-.52,-.61,;-.52,-2.15,;-1.86,.16,;-3.19,-.61,)|
Show InChI InChI=1S/C20H23Cl2N5O/c1-4-27(5-2)10-9-23-20-24-12-13-11-14(19(28)26(3)18(13)25-20)17-15(21)7-6-8-16(17)22/h6-8,11-12H,4-5,9-10H2,1-3H3,(H,23,24,25)
PDB
MMDB

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Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...

J Med Chem 43: 3134-47 (2000)


Article DOI: 10.1021/jm000148t
BindingDB Entry DOI: 10.7270/Q2028PQ1
More data for this
Ligand-Target Pair