Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50446314'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50446314 (CHEMBL3109348) Show SMILES COCCOc1ccn2c(cnc2c1)-c1ccc2cccc(O[C@H]3CC[C@H](N)CC3)c2n1 |r,wU:26.28,wD:23.24,(30.19,-22.56,;31.74,-22.58,;32.49,-23.91,;34.04,-23.93,;34.79,-25.28,;36.34,-25.29,;37.28,-26.52,;38.79,-26.32,;39.38,-24.91,;40.83,-24.4,;40.8,-22.86,;39.33,-22.41,;38.46,-23.68,;36.93,-23.88,;42.17,-25.17,;42.17,-26.71,;43.51,-27.49,;44.84,-26.71,;46.18,-27.48,;47.52,-26.7,;47.51,-25.15,;46.17,-24.39,;46.16,-22.84,;47.48,-22.08,;48.8,-22.86,;50.13,-22.1,;50.15,-20.57,;51.48,-19.81,;48.82,-19.79,;47.48,-20.55,;44.84,-25.16,;43.5,-24.4,)| Show InChI InChI=1S/C25H28N4O3/c1-30-13-14-31-20-11-12-29-22(16-27-24(29)15-20)21-10-5-17-3-2-4-23(25(17)28-21)32-19-8-6-18(26)7-9-19/h2-5,10-12,15-16,18-19H,6-9,13-14,26H2,1H3/t18-,19-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...				ACS Med Chem Lett 5: 78-83 (2014) Article DOI: 10.1021/ml4003953 BindingDB Entry DOI: 10.7270/Q23N24VQ
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