Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6596'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6596 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl propanoate...) Show SMILES CCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C20H16N2O3/c1-2-19(23)25-14-7-8-16-13(9-14)11-18(22-16)20(24)17-10-12-5-3-4-6-15(12)21-17/h3-11,21-22H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
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