Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM7250'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM7250 ((3Z)-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]pyrrol-1-y...) Show SMILES O=C1Nc2cccc(C3CCNCC3)c2\C1=C\c1[nH]cc2c1CCOC2=O Show InChI InChI=1S/C21H21N3O3/c25-20-15(10-18-14-6-9-27-21(26)16(14)11-23-18)19-13(2-1-3-17(19)24-20)12-4-7-22-8-5-12/h1-3,10-12,22-23H,4-9H2,(H,24,25)/b15-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	25
SUGEN, Inc.					Assay Description IC50 is the inhibitor concentration which inhibits 50% of PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well microtit...				Bioorg Med Chem Lett 13: 1939-42 (2003) Article DOI: 10.1016/s0960-894x(03)00312-3 BindingDB Entry DOI: 10.7270/Q2HD7SW7
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